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Tue, 28 Jul 2015
An Electrostatic Funnel in the GABA-Binding Pathway
The GABA receptor (GABAR) is a major inhibitory neuroreceptor that is activated by the binding of GABA (γ-aminobutyric acid). The structure of the GABAR is well characterized and many of the binding site... more »

Thu, 09 Jul 2015
Understanding the consequences of rare human genetic variation and susceptibility to pathogens
Progress in sequencing of the human genome identifies pathogenic and truncating variants in a large proportion of human genes. ... more »