RESEARCH DIVISIONS

  • Biomolecular Function Discovery Division

    Head of Division: Dr. Eisenhaber Frank
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    Biomolecular Function Discovery Division

    Functional interpretation of genome data in terms of biomolecular mechanisms is the major task in fundamental life science. Research results in this area will boost mechanistic research in other areas such as cell biology, genetics, immunology and disease-oriented fields. Gene function determination is a first and necessary step towards systematic understanding of biological systems.

  • Biomolecular Modelling and Design Division

    Head of Division: Dr. Verma Chandra
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    Biomolecular Modelling and Design Division

    The Biomolecular Modelling and Design Group is involved in unraveling the fundamental links between sequence, structure, dynamics and biological functions of molecules such as proteins. Recent advances in computational approaches, in conjunction with data obtained from various experimental techniques, have provided detailed atomistic insights into biological complexity. The group's approach follows this philosophy - to be tightly coupled to experimental laboratories such that testable hypotheses are generated and a feedback mechanism of predictions and validations exists between the groups. The group is highly interdisciplinary in origin and approach and works extensively with experimental and clinical partners and with the pharma industry.

  • Imaging Informatics Division

    Head of Division: Dr. Lee Hwee Kuan
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    Imaging Informatics Division

    The four groups of the Imaging Informatics division are dedicated to the field of quantitative microscopy which aims to automate the interpretation of images by applying methods in computer vision, machine learning and statistics. The research groups focus on "Computer Vision and Pattern Discovery", "Complex Cellular Phenotype Analysis", "Machine Learning For Bioimage Analysis" and "Biophysical Modelling".

  • Translational Research Division

    Head of Division: Dr. Ng Siew Bee
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    Translational Research Division

    The Natural Product Biology and Natural Product Chemistry groups jointly explore the chemical and genetic diversity of the plants and microbes within the A*STAR Natural Product Library to discover new bioactive compounds and enzymes for industrial application. The Chemical Genomics group uses chemical genetic tools in Saccharomyces cerevisiae (budding yeast) to uncover targets of bioactive compounds, reveal functions of genes and identify inhibitors of Protein-Protein Interactions. Started as a joint BII-p53Lab in Oct 2013, Antibody & Product Development (APD) Lab worked on Antibody Engineering, Viral drug resistance, Drug development, Scientific Phone Apps, IoT devices, Psychology, Augmented Reality, and psychology game apps.

  • Innovations in Food & Chemical Safety Programme

    Head of Division: Dr. Benjamin Smith
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    Innovations in Food & Chemical Safety Programme

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CROSS-DIVISION PROGRAMMES

  • Bioinformatics Platform for Clinicians and Industry

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  • Human Infectious Diseases

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