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Tue, 27 Jun 2017
Discovery, mechanism of action, biosynthesis and bioengineering of antibiotics from Gram-negative bacteria
The overwhelming majority of antibiotics in clinical use are natural products or semi-synthetic derivatives produced by Gram-positive Actinobacteria and filamentous fungi. Pathogenic microorganisms are becoming increasingly resistant to these compounds, and there is thus an urgent need to discover novel antibiotics to address the emerging health threat this poses.... more »