Imaging Informatics Division

The Bioinformatics Institute (BII) is a member of the Agency for Science, Technology and Research (A*STAR) Biomedical Sciences Institutes in Singapore. As a national research and postgraduate training institute in computational biology, the BII focuses on theoretical approaches aimed at understanding biomolecular mechanisms that underlie biological phenomena, the development of computational methods to support this discovery process, and experimental verification of predicted molecular and cellular functions of genes and proteins with biochemical methods.

Positions Available

 Research Officer (Biological Sciences/Bioengineering)

A Research Officer position in the areas of biological sciences or bioengineering is available in the Loo lab at the Bioinformatics Institute (BII), A*STAR, Singapore. The group is interested in studying chemical-induced toxicity using quantitative data modeling and cellular imaging methods. The group has recently developed the first high-throughput cellular imaging and computational platform for predicting kidney toxicity.

The successful candidate will be part of an interdisciplinary team that develops novel in vitro and computational models for predicting the toxicity of food ingredients, industrial chemicals, environmental pollutants, and drugs. He/she will develop and validate in vitro chemical testing assays based on human cells. The work will involve cell culture, fluorescence microscopy imaging, literature research, and molecular biology experiments. The candidate will also be responsible for managing lab reagents/equipment and other administration tasks. The candidate will have the opportunity to work in a highly stimulating environment, and participate in a global effort to develop next-generation and animal-free technologies for chemical safety assessment.


  1. MSc or BSc in biological/life sciences, molecular and cell biology, pharmacy/pharmacology, biomedical engineering, chemistry, chemical engineering, or other related disciplines
  2. At least two year of laboratory experience in mammalian cell culture and/or molecular biology experiments
  3. Past experience in high-throughput chemical screening, fluorescent microscopy, or bioinformatics is highly desirable, but not required
  4. Strong problem-solving skills, and able to work independently

Application Procedures: Applicants should send a one-page cover letter briefly describing prior research/work experience and accomplishments, and a full resume with contact information for two referees to Dr. Loo Lit Hsin (

Only shortlisted candidates will be notified.

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