CAREER OPPORTUNITIES AT BII

The Agency for Science, Technology and Research (A*STAR) is Singapore's lead public sector agency that fosters world-class scientific research and talent to drive economic growth and transform Singapore into a vibrant knowledge-based and innovation driven economy. In line with its mission-oriented mandate, A*STAR spearheads research and development in fields that are essential to growing Singapore's manufacturing sector and catalysing new growth industries. A*STAR supports these economic clusters by providing intellectual, human and industrial capital to its partners in industry.

A*STAR oversees 18 biomedical sciences and physical sciences and engineering research entities, located in Biopolis and Fusionopolis, as well as their vicinity. These two R&D hubs house a bustling and diverse community of local and international research scientists and engineers from A*STAR's research entities as well as a growing number of corporate laboratories.

Please proceed to the A*STAR Career Portal for the updated list of availble positions we have in Bioinformatics Institute (BII).

Positions are available until filled and only shortlisted candidates will be notified.

Description

A Research Officer position in the areas of proteomics is available in the Loo lab at the Bioinformatics Institute (BII), A*STAR, Singapore. The successful candidate will be part of an interdisciplinary team that develops novel in vitro and computational models for predicting the toxicity of food ingredients, industrial chemicals, environmental pollutants, and drugs. He or she will be involved in protein mass spectrometry analysis, molecular biology experiments and assist in laboratory procurement etc.

Job Requirements:

  1. B.Sc or M.Sc in life science disciplines, biomedical engineering, chemical engineering or analytical chemistry.
  2. At least two years of working experience in a laboratory setting, preferably in areas of mass spectrometry, protein science, biochemistry or analytical chemistry
  3. Experience with protein mass spectrometry will be preferred.
  4. Keen interest to pick up new technical skills and acquire new knowledge
  5. Able to work independently

Application Procedures:

Applicants should send the following documents to Dr. Loo Lit Hsin (loolh@bii.a-star.edu.sg). Only shortlisted candidates will be notified.

  1. A one-page cover letter briefly describing prior research experience and accomplishments.
  2. Resume, and
  3. Contact information of two references.

Our lab is engaged in research on the relation between structure and function of RNA. We combine information obtained by high-throughput sequencing, structure prediction tools, bioinformatic analysis and biochemical experiments to understand what structural elements in coding and non-coding RNAs contribute to gene regulation. We work on viral and human genomes. (for an example of our recent work: Link). We are looking for a motivated postdoc with a background in bioinformatics and an understanding of structural biology to join our team at the Bioinformatics Institute(BII) at A*STAR in Singapore.

We are looking for the following qualifications:

  1. PhD in Bioinformatics or Related Fields
  2. Understanding of Structural Biology (particularly RNA)
  3. Strong Statistical Skills
  4. Programming Experience (particularly Python)
  5. Verbal and Written Communications Skills
  6. Track Record of Published Research

Application Procedures:

A*STAR offers a competitive compensation package and relocation assistance. Interested applicants can contact me at rghuber@bii.a-star.edu.sg in case of any questions. Otherwise I would like to ask to submit a CV and cover letter to the above email address. Shortlisted candidates will be asked to provide contact details and letters of reference from 2-3 referees.

The lab of Igor Berezovsky at the Bioinformatics Institute is looking for highly motivated postdoctoral researcher in Computational Biophysics/Bioinformatics.

The project is a continuation of the group's innovative work in the field of protein allosteric regulation (PLOS Comp Biol 12, e1004678 (2016), Curr Opin Struct Biol 37, 1 (2016), Bioinformatics 33, 3996 (2017), PLOS Comp Biol 14, e1006228 (2018), Nucl Acids Res 47, D265 (2019), Curr Opin Struct Biol 56, 18 (2019), Structure 27, 866 (2019)). It includes a work on the molecular model of allosteric regulation with the focus on inducing required allosteric signaling, exploring and tuning effects of the ligand-binding, and developing in silico approaches for the design of allosteric drugs. Collaboration with experimental groups on the validation of computational predictions will also be continued (Biochemistry 56, 228 (2017)).

The candidate should have a strong background in physics and mathematics, biophysics, bioinformatics and computational biology, structural biology, or computational sciences. Previous experience in physics, computer science, bioinformatics or applied statistics will be a plus. The candidate should also possess strong quantitative skills and be highly proficient in at least one major programming language, including Python or C/C++.

Applications containing the following should be sent by e-mail to Group Leader Igor N. Berezovsky:

  1. A letter of motivation with statement of research interests
  2. Curriculum Vitae
  3. Names and Contact information of two references

The three-year position is available from September 2019.

The Bioinformatics Institute (BII) is a member of the Agency for Science, Technology and Research (A*STAR) Biomedical Sciences Institutes. Funded by Biomedical Research Council (BMRC) of A*STAR, BII was set up in July 2001 as part of the national initiative to foster and advance biomedical research and human capital for a vibrant knowledge-based Singapore. BII aims to be a premier international institute in Bioinformatics by fostering and conducting leading-edge informatics research and development, providing high quality training and generating knowledge from large diverse volumes of biology, chemistry and medical data.

BII is located in the Biopolis, Singapore's premier hub for Biomedical Sciences. The Biopolis is dedicated to providing facilities for R&D activities and an environment that fosters a collaborative culture amongst the private and public research institutes.

The candidate should have a strong background in physics and mathematics, biophysics, bioinformatics and computational biology, structural biology, or computational sciences. Previous experience in physics, computer science, bioinformatics or applied statistics will be a plus. The candidate should also possess strong quantitative skills and be highly proficient in at least one major programming language, including Python or C/C++.

Research Officer

A Research Officer position is available in the Analytics of Biological Sequence Data (ABSD) group under the Biomolecular Function Discovery (BFD) Division of BII. The research group is led by Dr. Wing Cheong Wong. The candidate will support the development of a web based medical informatics system that manages clinical data (clinical and OMICS measures) from multiple sites.

Responsibilities

  • Support the team in the building of computational pipelines and web interface for a clinical management system. This involves testing, replicating and modifying the necessary computational algorithms.
  • Perform data management (including collection, quality check, versioning) of clinical data sets
  • Carrying out mini projects to demonstrate proof of concept for new research ideas.

Requirements

  • Bachelor’s degree in Computer Science/Computer Engineering/Information Technology or related fields
  • Well versed in programming methodology with good understanding in numerical methods and statistics
  • Independent and highly-motivated

Please email your applications to wongwc@bii.a-star.edu.sg. Only shortlisted candidates will be contacted.