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Fri, 29 Apr 2016
Structural Basis for Immune Recognition of Intrinsically Disordered Vaccine Candidates
Intrinsically disordered proteins are highly abundant in pathogenic organisms. Our bioinformatic analyses show that disordered antigens can be very effective antigens. Little is known, however, about the implications of protein disorder for the development of a protective immune response. We have undertaken a detailed analysis of the conformational dynamics of MSP2... more »