Senior Principal Investigator
   Research Group: Biophysical Modelling

CHIAM Keng Hwee is a theorist working at the interface of physics and biology, collaborating very closely with experimental groups in developing theories and models for a variety of problems in mechanobiology and biological physics, systems biology, and biological fluid mechanics. He received his Ph.D. in physics from the California Institute of Technology in 2003 and his B.S.E. in physics from the University of Michigan in 1997. Prior to joining the Bioinformatics Institute in 2013, he and his group was located at the Institute of High Performance Computing.

Keng Hwee's group uses a combination of biophysical and bioinformatics tools to study cell migration. Cell migration is a critical process in every living organism, central to, for example, the morphogenesis of embryos, formation of tissues and organs, wound repair, as well as in less welcoming scenarios such as cancer metastasis. Some of their current projects include the study of amoeboid modes of cancer cell invasion, collective modes of epithelial cell sheet migration, and swimming and swarming modes of bacterial cell motility.

He hopes that their approach will enable them to identify potential targets to perturb cell migration, which can eventually be translated into drugs to stop cancer cell invasion, promote wound and skin healing, or stop the aggregation of bacterial cells into biofilms.

Biophysical Modeling Members

Dr. CHIAM Keng Hwee
Principal Investigator
  Biography Details
  Lab Website
Dr. CHIAM Keng HweePrincipal Investigator
Dr. ZENG YukaiPostdoctoral Fellow
Dr. YIP Ai KiaPostdoctoral Fellow
Ms. FARM Hui JiaResearch Officer

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