FAN HAO

Principal Investigator
  fanh@bii.a-star.edu.sg
   Research Group: Structure-based Ligand Discovery and Design


Dr. Hao Fan was appointed Principal Investigator at the Bioinformatics Institute (BII), A*STAR in February 2014. The broad goal of his group is to develop computational techniques to facilitate ligand discovery in the superfamily/genome scale. The developed methods will be applied to families of uncharacterized enzymes and therapeutic targets such as GPCRs and kinases, to contribute to a better understanding and regulation of biological processes, as well as the discovery of new drugs. The computational predictions will be tested experimentally through collaborations. Prior to joining Singapore, he worked as a postdoctoral fellow followed by a research scientist in both Dr. Andrej Sali's lab and Dr. Brian Shoichet's lab at University of California, San Francisco (UCSF). He obtained his Ph.D in Biophysical Chemistry in Dr. Alan Mark's lab at University of Groningen (RUG). He received his undergraduate degree in Biological Sciences in University of Science and Technology of China (USTC).

The broad goal is to develop computational techniques to effectively and accurately model protein-ligand interactions, the developed methods will be applied to therapeutic targets such as GPCRs, transporters and downstream kinases, to contribute to a better understanding and regulation of biological processes, to the discovery of new ingredients for food and nutrition, chemical probes, and drug leads, and to the development of an in-silico platform for chemical toxicity prediction.

Structure-based Ligand Discovery and Design Members

Dr. FAN Hao
Principal Investigator
 
  Biography Details
NameTitle
Dr. FAN HaoPrincipal Investigator
Dr. VERMA Ravi KumarPostdoctoral Fellow
Dr. LIN FuPostdoctoral Fellow
Dr. HARTONO Yossa DwiPostdoctoral Fellow
Dr. JALADANKI Chaitanya KumarPostdoctoral Fellow
Dr. Krishna DeepakPostdoctoral Fellow
Ms. LO Wing Kwan Catharine ( joint with Dr. Cheng Li's lab )Research Officer
Mr. MASIREVIC Srdjan PhD student
Mr. LIM Jie Han, Kevin PhD student
Mr. Alessandro BARBIERI PhD student

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