Principal Investigator
   Research Group: Chemical Genomics

Prakash Arumugam joined the Translational Research division of BII in January 2015. He completed his doctoral work at the Centre for Cellular and Molecular Biology in India in 2001. During his PhD, he showed that the human lamin B receptor has sterol biosynthetic activity. He joined Prof. Kim Nasmyth's laboratory at the Institute of Molecular Pathology (IMP) in Vienna as a postdoctoral fellow in 2002 and elucidated the role of cohesin's ATPase activity in sister chromatid cohesion in budding yeast. He joined the University of Warwick in the UK as a lecturer in 2007 and established his independent laboratory to study meiotic cell cycle and chromosome segregation in budding yeast. His group identified the first binding site for monopolins at the kinetochore, and a conserved signalling module (Rim15-PP2ACdc55-Endosulfine) that regulates entry into gametogenesis, in budding yeast.

My laboratory uses chemical genetic tools in yeast and mammalian cells to uncover mode-of action of bioactive compounds, map cellular pathways of toxicity, determine functions of conserved protein complexes and screen for inhibitors of Protein-Protein interaction.

Chemical Genomics Members

Dr. Prakash ARUMUGAM
Principal Investigator
  Biography Details
Dr. ARUMUGAM PrakashPrincipal Investigator
Dr. Mohammad AlfatahPostdoctoral Fellow
Ms. WONG Jin HueiResearch Officer
Ms. GOH Jie Hui, CorinnaResearch Officer
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