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Dr. LEE Hwee Kuan
Principal Investigator
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| Areas of Research Interest |
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| Lee Hwee Kuan's current research focuses on for analysis of live cells images. These images are obtained from wide-field and confocal microscopy, including image data sets from high-throughput screens. His group's efforts contribute to the trend towards quantitative biology, in which scientific hypothesis are based on statistically significant objective data. |
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| Biography |
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| Lee Hwee Kuan is a Principal Investigator of the Imaging Informatics division in Bioinformatics Institute. His current research work involves developing and deployment of computer vision aglorithms for high throughput bioimaging experiments. Hwee Kuan obtained his Ph.D. in 2001 in Theoretical Physics from Carnegie Mellon University, he was working on Monte Carlo simulations of liquid-liquid phase transitions and quasicrystals. He then held a joint postdoctoral position with Oak Ridge National Laboratory (USA) and University of Georgia where he worked on developing advanced Monte Carlo methods and nano-magnetism. In 2003, with an award from the Japan Society for Promotion of Science, Hwee Kuan moved to Tokyo Metropolitan University where he developed solutions to extremely long time scaled problems and a reweighting method for nonequilibrium systems. In 2005 he returned home to join Data Storage Institute, investigating novel recording methods such as hard disk recording via magnetic resonance. In 2006, he joined Bioinformatics Institute as a Principle Investigator in the Imaging Informatics Division. |
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| Selected Publications |
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- Yan Nei Law, Hwee Kuan Lee and Andy M. Yip
A Multi-resolution Stochastic Level Set Method for Mumford-Shah Image Segmentation
IEEE Trans. Img. Proc. (Accepted); UCLA CAM Report 07-43 (2007) http://www.math.ucla.edu/applied/cam/
- Y. N. Law, S. Ogg, et al.
Automated Protein Distribution Detection in High-Throughput Image-Based siRNA Library Screens
J. Sign. Process. Syst. (Accepted and Published online)
- Cheng XZ, Jalil MB, Lee HK.
Analytical solution to transport in Brownian ratchets via the gambler's ruin model.
Phys Rev Lett. 2007 Aug 17;99(7):070601. Epub 2007 Aug 16.
PMID: 17930880 [PubMed]
- Lee HK, Yuan Z.
Studies of the Magnetization Reversal Process Driven by an Oscillating field
J. Appl. Phys. 2007; 101: 033903
- Cheng XZ, Jalil MB, Lee HK.
Micromagnetic study on Thermally Induced Magnetization Reversal of Coupled Spin Chain System
IEEE Trans. Magn. 2007; 43: 2899
- Cheng XZ, Jalil MB, Lee HK, Okabe Y.
Mapping the Monte Carlo scheme to Langevin dynamics: a Fokker-Planck approach.
Phys Rev Lett. 2006 Feb 17;96(6):067208. Epub 2006 Feb 17.
PMID: 16606044 [PubMed]
- Lee HK, Okabe Y.
Exchange Bias with Interacting Random Anti-ferromagnetic Grains
Phys. Rev. B 2006; 73: 140403
[arXiv:cond-mat/0603780]
- Lee HK, Okabe Y, Landau DP.
Convergence and Refinement of the Wang-Landau Algorithm
Comp. Phys. Comm. 2006; 175: 36
[arXiv:cond-mat/0506555]
- Lee HK, Okabe Y.
Multispin Coding Technique for Nonequilibrium Reweighting
Int. J. Mod. Phys. C 2006; 17: 157
[arXiv:cond-mat/0603788]
- Cheng XZ, Jalil MB, Lee HK.
Time-quantified Monte Carlo Algorithm for Interacting Spin Array Micromagnetic Dynamics
Phys. Rev. B 2006; 73: 2244338
- Cheng XZ, Jalil MB, Lee HK, Okabe Y.
Precessional and Thermal Relaxation Dynamics of Magnetic Nanoparticles - A Time-Quantified Monte Carlo Approach
J. Appl. Phys. 2006; 99: 08B901
- Xiao P, Yuan Z, Lee HK, Guo G.
Bit-array Alignment Effect of Perpendicular SOMA Media
J. Magn. Magn. Mater. 2006; 303: e6-e10
- Xiao P, Yuan Z, Lee HK, Guo G.
Ring Head and Single Pole Head Recording Performance on 3D Random SOMA Media
J. Magn. Magn. Mater. 2003; 303: e29-e33
- Lee HK, Okabe Y.
Nonequilibrium Reweighting on Driven Diffusive Lattice Gas
J. Phys. A: Math. Gen. (Lett) 2005; 38: L241
[arXiv:cond-mat/0503324]
- Lee HK, Okabe Y.
Reweighting for nonequilibrium Markov processes using sequential importance sampling methods.
Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Jan;71(1 Pt 2):015102. Epub 2005 Jan 7.
PMID: 15697640 [PubMed]
- Lee HK, Okabe Y, Cheng XZ, Jalil MB
Solving the Master Equation for Extremely Long Time Scale Calculations
Comp. Phys. Comm. 2005; 168:159
[arXiv:cond-mat/0412151]
- Cheng XZ, Jalil MB, Lee HK, Okabe Y.
Time Quantifiable Monte Carlo Method in Simulating Magnetization Reversal Process
Phys. Rev. B 2005; 72: 094420
[arXiv:cond-mat/0504358]
- Tsai SH, Lee HK, Landau DP.
Molecular and Spin Dynamics Simulations using Symplectic Integration Methods
Amer. J. Phys. 2005; 73: 615
- Brown G, Lee HK, Schulthess TC.
C++ and Generic Programming for Rapid Development of Monte Carlo Simulations
Computer Simulation Studies in Condensed-matter Physics XVII (Ed. D. P. Landau, S. P. Lewis and H.-B. Schuttler) Springer, Berlin 2004
- Lee HK, Schulthess TC, Brown G, Landau DP, Sorge KD, Thompson JR.
Magnetic Properties of Fe Nano-cubes with Magnetostatic Interactions
J. Appl. Phys. 2003; 93: 7047
- Lee HK, Landau DP, Schulthess TC
Monte Carlo Simulations of Phase Transitions in Rb2MnF4
J. Appl. Phys. 2003; 93: 7643
- Lee HK, Schulthess DP, Landau DP, Brown G, Pierce JP, Gai Z, Farnam G, Shen J.
Monte Carlo Simulations of Interacting Mangetic Nanoparticles
J. Appl. Phys. 2002; 91: 6926
- Brown G, Lee HK, Schulthess TC, Ujfalussy G, Stocks GM, Butler WH, Landau DP, Pierce JP, Shen J, Kirschner J.
Model of Fe Nanostripes on Cu(111)
J. Appl. Phys. 2002; 91: 7056
- Lee HK, Swendsen RH
Simple Model of Liquid-liquid Phase Transition
Phys. Rev. B 2001; 64: 214102
[arXiv:cond-mat/0106617]
- Lee HK, Swendsen RH, Widom M.
Crystalline Ground States of An Entropically Stablized Quasicrystal Model
Phys. Rev. B 2001; 64: 224201
- Qin L, Shen ZX, Low BL, Lee HK, et al.
Crystallization Study of Heavy Metal Fluoride Glasses ZBLAN by Raman Spectroscopy
J. Raman Spect. 1997; 28: 495
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Please contact us by email if you wish a reprint from any of the selected publications. |
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