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  Biography Details
 
Dr. Martin WASSER
Principal Investigator
 
Areas of Research Interest
 
  • Cell and Developmental Biology
  • 3D Time-Lapse microscopy
  • Computer Vision
  • Artificial Intelligence
 
Biography
 
Martin Wasser studied biology at the University of Cologne in Germany. In 1993, he graduated with the degree of 'Diplombiologe' after completing his thesis work at the Institute of Developmental Biology under supervision of Prof. J. Campos-Ortega. In the same, year he joined the laboratory of Prof. William Chia at the Institute of Molecular and Cell Biology (IMCB) in Singapore where he obtained his PhD in 1998. During his postdoctoral years at the IMCB and the Temasek Life Sciences Laboratory (TLL), he continued his research on the role of nuclear architecture in cell cycle and development using the fruit fly Drosophila as a model. In his research, he discovered the importance of live cell microscopy in studying gene and protein function. Realizing that all his training as a wet-lab had not equipped him with the skills to deal with the data explosion in the life sciences, he decided to pursue a part-time degree in knowledge engineering at the Institute of Systems Science (ISS). In 2004, he obtained the Master in Technology and was awarded the prize for the best project in Knowledge Engineering. He designed an expert system for automated recognition and classification of Drosophila chromosomes in microscopic images. In 2007, he joined the BII as a Principal Investigator to head a research team in the division of Imaging Informatics.
 
Selected Publications
 
  1. Wasser M, Bte Osman Z, Chia W.
    EAST and Chromator control the destruction and remodeling of muscles during Drosophila metamorphosis.
    Dev Biol. 2007 Jul 15;307(2):380-93. Epub 2007 May 6.


  2. Wasser M, Chia W.
    The extrachromosomal East protein of Drosophila can associate with polytene chromosomes and regulate gene expression.
    PLoS ONE. 2007 May 2;2(5):e412.


  3. Wasser M, Chia W.
    The Drosophila EAST protein associates with a nuclear remnant during mitosis and constrains chromosome mobility.
    J Cell Sci. 2003 May 1;116(Pt 9):1733-43.


  4. Wasser M, Chia W.
    The EAST protein of drosophila controls an expandable nuclear endoskeleton.
    Nat Cell Biol. 2000 May;2(5):268-75.


  5. Li P, Yang X, Wasser M, Cai Y, Chia W.
    Inscuteable and Staufen mediate asymmetric localization and segregation of prospero RNA during Drosophila neuroblast cell divisions.
    Cell. 1997 Aug 8;90(3):437-47.
 

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