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Dr. Mallur Srivatsan MADHUSUDHAN
Principal Investigator
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| Group Members |
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| Name | Title |
| Dr. Mallur Srivatsan MADHUSUDHAN |
Principal Investigator |
| Dr. Nguyen Ngoc Minh |
Postdoctoral Fellow |
| Ms. CHEONG Wai Sim, Rowena |
Research Associate |
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Research Overview
Our aim is to accurately model the 3D structures of proteins and their complexes. To this end, we combine the laws of physics along with experimental observation and statistics to develop computational methods in structural biology. The methods are tested, often in close collaboration with experimental biologists, on particular systems of interest. Our research gives detailed information of cellular processes and hence impacts research on human health, nutrition and biology as a whole.
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| More Details |
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| Selected Publications |
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- Davis FP, Braberg H, Shen MY, Pieper U, Sali A, Madhusudhan MS.
Protein complex compositions predicted by structural similarity.
Nucleic Acids Res. 2006 May 31;34(10):2943-52. Print 2006.
PMID: 16738133 [PubMed - indexed for MEDLINE]
- Madhusudhan MS, Marti-Renom MA, Sanchez R, Sali A.
Variable gap penalty for protein sequence-structure alignment.
Protein Eng Des Sel. 2006 Mar;19(3):129-33. Epub 2006 Jan 19.
PMID: 16423846 [PubMed - indexed for MEDLINE]
- Bajaj K, Madhusudhan MS, Adkar BV, Chakrabarti P, Ramakrishnan C, Sali A, Varadarajan R.
Stereochemical criteria for prediction of the effects of proline mutations on protein stability.
PLoS Comput Biol. 2007 Dec;3(12):e241.
PMID: 18069886 [PubMed - in process]
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